SR calcium handling dysfunction, stress-response signaling pathways, and atrial fibrillation
نویسندگان
چکیده
منابع مشابه
SR calcium handling dysfunction, stress-response signaling pathways, and atrial fibrillation
Atrial fibrillation (AF) is the most common sustained arrhythmia. It is associated with a markedly increased risk of premature death due to embolic stroke and also complicates co-existing cardiovascular diseases such as heart failure. The prevalence of AF increases dramatically with age, and aging has been shown to be an independent risk of AF. Due to an aging population in the world, a growing...
متن کاملAtrial Fibrillation-Promoting Effect of Altered Left Atrial Calcium-Handling Proteins in Heart Failure
Background and Objectives: The incidence of atrial fibrillation (AF) is increased in heart failure (HF). Two major mechanisms of ventricular arrhythmia in HF are reentry mechanism due to tissue fibrosis and triggered activity due to an altered calcium-handling process. Unlike studies on ventricular arrhythmogenesis, only few studies investigated the relationship between changes in the calcium-h...
متن کاملAge-related changes in cellular electrophysiology and calcium handling for atrial fibrillation
This study was to investigate whether or not the dysfunction of atrial repolarization and abnormality of the intracellular Ca(2+) handling protein was augmented with ageing. Four groups of dogs were studied, adult and aged dogs in sinus rhythm (SR) and atrial fibrillation (AF) induced by rapid atrial pacing. We used whole cell patch clamp recording techniques to measure L-type Ca(2+) current in...
متن کاملAtrial fibrillation and sinus node dysfunction.
1. Marcovina SM, Albers JJ, Scanu AM, et al. Use of a reference material proposed by the International Federation of Clinical Chemistry and Laboratory Medicine to evaluate analytical methods for the determination of plasma lipoprotein(a). Clin Chem 2000;46:1956–67. 2. Seman LJ, DeLuca C, Jenner JL, et al. Lipoprotein(a) cholesterol and coronary heart disease in the Framingham Heart Study. Clin ...
متن کاملchemical cardioversion of atrial fibrillation with calcium gluconate
background calcium infusion is used as a pre-treatment before calcium channel blockers to prevent hypotension. occasional cardioversion with calcium gluconate infusion is seen in patients with paroxysmal supraventricular tachycardia. several mechanisms have been suggested for mechanism. herein we report a case presenting with atrial fibrillation but cardioverted with calcium gluconate infusion,...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Physiology
سال: 2015
ISSN: 1664-042X
DOI: 10.3389/fphys.2015.00046